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maioADHD Medication Pregnancy: The Good, The Bad, And The Ugly
ADHD Medication During Pregnancy and Breastfeeding
Women with ADHD have to make a difficult choice on whether to keep or stop taking ADHD medication during pregnancy and breast-feeding. There aren't many studies regarding how exposure over time may affect a foetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication in utero do not develop neurological disorders such as hearing loss or impaired vision, febrile seizures, or IQ impairment. The authors acknowledge that more high-quality studies are needed.
Risk/Benefit Analysis
Women who are pregnant and take ADHD medication must evaluate the benefits of using it versus the dangers for the baby. Physicians do not have the data needed to give clear guidelines however they can provide information about the risks and benefits to help pregnant women make informed decisions.
A study published in Molecular Psychiatry concluded that women who took does adhd medication work medication during early pregnancy did not have a greater risk of fetal malformations, or structural birth defects. The researchers used a large, population-based case-control study to determine the prevalence of major structural birth defects in babies born to mothers who had taken stimulants during early pregnancy, and those who did not. Clinical geneticists and pediatric cardiologists reviewed the cases to ensure correct classification of the cases and to reduce the chance of bias.
However, the researchers' study was not without its flaws. The researchers were not able, in the first place to differentiate the effects triggered by the medication from the disorder. This makes it difficult for researchers to establish whether the small differences observed between the groups that were exposed to the use of medications, or if they were affected by co-morbidities. In addition, the researchers did not study the long-term outcomes of offspring.
The study did reveal that infants whose mothers had taken ADHD medications during pregnancy were at slightly higher risk of being admitted to the neonatal intensive care unit (NICU) than infants who were born without any medication or had taken off their medication prior to or during pregnancy. This was due to central nervous system disorders. The higher risk of admission was not influenced by the stimulant medications used during pregnancy.
Women who were taking stimulant ADHD medication during pregnancy were also at an elevated risk of having a caesarean birth or having a baby born with an low Apgar score (less than 7). These increases appear to be independent of the type of medication taken during pregnancy.
The research suggests that the small risk associated with the use of ADHD medications during the early stages of pregnancy could be offset by the higher benefit to both mother and child of continued treatment for the woman's condition. Physicians should discuss this with their patients and, if they are able, assist them in developing strategies to improve their coping abilities which can reduce the impact of her disorder on her daily life and relationships.
Interactions with Medication
Doctors are increasingly confronted with the dilemma of whether to maintain treatment or stop it during pregnancy as more women are diagnosed with ADHD. Most of the time, these decisions are made in the absence of any evidence that is clear and definitive regardless, so doctors must weigh what they know about their experiences, the experiences of other doctors, and what research suggests on the subject as well as their best judgment for each individual patient.
Particularly, the issue of potential risks to the baby can be tricky. Many studies on this issue are based on observational data instead of controlled research and their conclusions are often contradictory. The majority of studies focus on live births, which can underestimate the teratogenic impact that can lead to terminations or abortions of pregnancy. The study presented in this journal club addresses these shortcomings by looking at data from both live and deceased births.
Conclusion Some studies have revealed a positive correlation between ADHD medications and certain birth defects, other studies have not established a link. The majority of studies show a neutral, or even somewhat negative, impact. In every case, a careful study of the benefits and risks should be conducted.
For many women with ADHD who suffer from adhd medication without diagnosis uk, the decision to stop taking medication can be difficult, if not impossible. In fact, in an article recently published in the Archives of Women's Mental Health psychologist Jennifer Russell notes that stopping Private Adhd Medication Cost medication during pregnancy can lead to increased depression, feelings of loneliness and family conflict for patients with ADHD. Additionally, the loss of medication may affect the ability to complete job-related tasks and drive safely that are crucial aspects of daily life genetic testing for adhd medications many people with ADHD.
She recommends that women who are unsure about whether to continue or discontinue medication due to their pregnancy, consider the possibility of educating friends, family members, and coworkers on the condition, its effects on daily life, and the benefits of keeping the current treatment regimen. In addition, educating them can aid in ensuring that the woman feels supported as she struggles with her decision. Certain medications can be passed through the placenta. If a patient decides to stop taking her ADHD medication while pregnant and breastfeeding, it is important to be aware that the drug may be transferred to her baby.
Risk of Birth Defects
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows, so do concerns about the effects that the drugs might have on fetuses. A recent study published in the journal Molecular Psychiatry adds to the existing knowledge on this subject. Utilizing two huge data sets researchers were able look at more than 4.3 million pregnancies to determine whether stimulant medication use increased the risk of birth defects. While the overall risk remains low, the researchers discovered that the first-trimester exposure to adhd medication in the uk medicines was associated with an increase in the risk of certain heart defects like ventriculo-septal defects (VSD).
The authors of the study found no association between early medication use and other congenital anomalies, like facial clefting, or club foot. The results are in line with previous studies revealing the presence of a small, but significant increase in the risk of heart malformations among women who began taking ADHD medications prior to pregnancy. This risk increased in the later part of pregnancy, when many women begin to discontinue their ADHD medication.
Women who used ADHD medication in the first trimester of their pregnancy were also more likely to experience a caesarean section, a low Apgar score following delivery, and a baby who required breathing assistance at birth. The authors of the study were unable to eliminate bias due to selection because they limited their study to women who did not have any other medical conditions that could have contributed to the findings.
The researchers hope their research will help inform the clinical decisions of doctors who treat pregnant women. They suggest that although discussing the risks and benefits is crucial however, the decision to stop or maintain treatment should be based on the woman's needs and the severity of her ADHD symptoms.
The authors also advise that even though stopping the medication is an option, it isn't an option to consider due to the high prevalence of depression and other mental health problems among women who are pregnant or recently postpartum. Further, research shows that women who stop taking their medication will have a difficult time adjusting to a life without them once the baby is born.
Nursing
It can be overwhelming to become a mother. Women who suffer from mild adhd medication can face severe challenges when they have to manage their symptoms, go to doctor appointments and prepare for the birth of a baby and adjust to a new routine. Many women decide to continue taking their ADHD medication during pregnancy.
The risk to a nursing infant is low because the majority of stimulant medications is absorbed through breast milk at low levels. The rate of medication exposure can vary depending upon the dosage, frequency of administration and time of day. In addition, different drugs enter the infant's system through the gastrointestinal tract or through breast milk. The effect on the health of a newborn is not fully understood.
Because of the lack of research, some physicians may recommend stopping stimulant drugs during the course of pregnancy. This is a difficult decision for the patient, who must weigh the benefits of continuing her medication against the possible risks to the foetus. As long as there is no more information, GPs should ask all pregnant patients about their experience with ADHD and whether they plan or are taking to take medication during the perinatal period.
Numerous studies have demonstrated that women can continue taking their ADHD medication in a safe manner during pregnancy and while breast-feeding. In response, a rising number of patients are choosing to continue their medication. They have concluded through consultation with their physicians that the benefits of keeping their current medication outweigh any risk.
Women with ADHD who plan to breastfeed should seek advice from an expert psychiatrist prior to becoming pregnant. They should review their medications with their prescriber and discuss the pros and cons of continued treatment, including non-pharmacological strategies. Psychoeducation is also necessary to help pregnant women with ADHD recognize the signs and underlying disorder. They should also be educated about treatment options and strengthen the coping mechanisms. This should involve a multidisciplinary approach with the GP doctors, obstetricians and psychiatrists. The pregnancy counselling should consist of discussion of a management plan for both mother and child, as well as monitoring for signs of deterioration and the need for adjustments to the medication regimen.
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